Vertical: CNMBase Year: 2025
Market Size (2025)
$132.94M
Projected (2032)
$187.51M
CAGR (2022–2032)
5.0%
Key Players
9+
Market Overview
The Global Mannan Oligosaccharides Market was valued at USD 132.94 million in 2025 and is projected to reach USD 187.51 million by 2032, registering a CAGR of 5.03% during 2026–2032. The market stood at USD 114.69 million in 2022, USD 120.48 million in 2023 and USD 126.56 million in 2024, and the absolute increase between 2025 and 2032 amounts to USD 54.57 million.
Mannan oligosaccharides (MOS) are prebiotic carbohydrates obtained mainly from the outer cell wall of the yeast Saccharomyces cerevisiae. In livestock and aquaculture diets they act by binding mannose-specific fimbriae of enteric pathogens such as Escherichia coli and Salmonella, which limits their attachment to the intestinal lining, and by supporting gut-associated immune function. Demand is shaped by the long-running shift away from antibiotic growth promoters, the expansion of intensive poultry, swine and aquaculture production, and growing attention to feed efficiency and pre-harvest food safety.
Growth over the forecast period is expected to be steady rather than rapid. Mature markets in Europe and North America are expected to grow at moderate rates as MOS use is already established there, while Asia Pacific, Latin America and the Middle East & Africa expand faster on the back of rising protein consumption, production intensification and tightening rules on antimicrobial use in feed.
Key Findings
Livestock: Poultry is the largest segment with USD 59.82 million in 2025 (45.00% share), while Aquaculture & Others is the fastest-growing segment at a CAGR of 5.78%.
Physical form: Powder dominates with USD 119.65 million in 2025 (90.00% share); Others grows fastest at a CAGR of 6.81%.
Region: Asia Pacific is the leading region with USD 42.54 million in 2025 (32.00% share) and is also the fastest-growing region at a CAGR of 6.24%.
Country: U.S. is the leading country with USD 22.23 million in 2025 (16.72% of the global market), while India is the fastest-growing country at a CAGR of 8.49%.
Growth increment: The market is expected to add USD 54.57 million between 2025 and 2032, of which Asia Pacific contributes USD 22.32 million, the largest absolute gain of any region.
Segmentation Summary
By livestock, the market is divided into Poultry, Swine and Aquaculture & Others. Poultry leads because broiler and layer production is the largest consumer of compound feed and because MOS has the longest record of commercial use and trial evidence in poultry diets. Swine holds the second-largest share, supported by its use in piglet and sow diets, but grows more slowly owing to mature swine sectors in Europe and North America. Aquaculture & Others, which also covers ruminants, companion animals and other species, is the fastest-growing segment as aquafeed producers adopt functional additives to manage disease pressure.
By physical form, Powder accounts for the bulk of demand because it blends readily into premixes and compound feed and remains stable during storage and pelleting. Other forms, including liquid, granulated, encapsulated and water-soluble products, are smaller but expand faster as producers adopt drinking-water application and more targeted formats.
Competitive Landscape Summary
The market is moderately consolidated. A small group of yeast and fermentation specialists, notably Alltech, Phileo by Lesaffre (which now includes Biorigin), Lallemand Animal Nutrition and Angel Yeast, supply a large part of branded MOS and yeast cell wall products worldwide. They are followed by companies such as ICC Brazil, Ohly (ABF Ingredients), Leiber (acquired by Asahi Group Foods), Arm & Hammer Animal and Food Production and Biochem, together with numerous regional producers in China, India and Latin America.
Competition centres on product consistency (guaranteed MOS and beta-glucan content), trial evidence by species, technical service to integrators and feed mills, and cost. Recent activity has been dominated by consolidation and capacity investment, including Lesaffre’s acquisition of a 70% stake in Biorigin, Asahi Group Foods’ agreement to acquire Leiber, Ohly’s capacity expansion in Hamburg and its planned North American campus, and Angel Yeast’s overseas yeast capacity additions in Egypt and Russia.
Challenges and Opportunities
The main challenges are variable efficacy across products and production conditions, which makes some buyers cautious; strong price sensitivity among feed mills and integrators during periods of high feed costs; and competition from alternative gut-health additives such as probiotics, organic acids, phytogenics and other prebiotics. Disease outbreaks such as African swine fever and highly pathogenic avian influenza can also reduce animal numbers and disrupt demand in affected countries.
Opportunities lie in aquaculture, particularly shrimp and fish farming in Asia and Latin America; in higher-value purified, soluble and combination products that support drinking-water application and synbiotic formulations; and in fast-growing livestock sectors in India, Southeast Asia, Africa and the Middle East, where commercial production and antimicrobial stewardship are both expanding.
Future Outlook
The Global Mannan Oligosaccharides Market is expected to grow from USD 139.65 million in 2026 to USD 187.51 million in 2032. Growth will be supported by continued restrictions on antimicrobial use in food-producing animals, structural growth in poultry and aquaculture, and a gradual move towards standardised, higher-purity yeast cell wall fractions. Asia Pacific is expected to remain both the largest and fastest-growing region, increasing from USD 42.54 million in 2025 to USD 64.87 million in 2032. Suppliers that combine reliable product specifications, species-specific trial data and local technical support are best placed to gain share.
The Mannan Oligosaccharides Market market is projected to grow at a CAGR of 5.0% from 2022 to 2032.
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View Subscription PlansDefinition
Mannan oligosaccharides (MOS) are short-chain and complex carbohydrates composed mainly of mannose units, typically linked to proteins as mannoproteins. Commercial MOS for animal nutrition is obtained predominantly from the outer layer of the cell wall of Saccharomyces cerevisiae yeast. The yeast may be primary-grown for the purpose or recovered as a co-product of brewing or sugarcane ethanol fermentation. After cell disruption (autolysis, plasmolysis or enzymatic hydrolysis), the cell wall fraction is separated, washed, concentrated and dried. The resulting product contains MOS together with beta-1,3/1,6-glucans, and suppliers increasingly guarantee minimum levels of both.
MOS is classed as a prebiotic feed ingredient. Its main mode of action is to provide mannose-rich binding sites that agglutinate bacteria carrying type-1 (mannose-specific) fimbriae, including many strains of E. coli and Salmonella, so that they pass through the gut instead of colonising it. MOS products are also associated with improved intestinal morphology and modulation of gut-associated immune responses. MOS can also be produced from plant mannans such as copra and palm kernel meal, konjac, guar and locust bean gum through enzymatic hydrolysis.
Included in the scope: MOS and MOS-rich yeast cell wall products used in feed and drinking water for poultry, swine, aquaculture and other animals (ruminants, companion animals, equine and other species), supplied in powder and other physical forms (liquid, granulated, encapsulated and water-soluble formats).
Excluded from the scope: whole live yeast and probiotic yeast products sold for their live-cell activity, yeast extracts used primarily as flavour or nutrient sources, purified beta-glucan products sold without MOS functionality, other prebiotic oligosaccharides (such as fructo-, galacto- and xylo-oligosaccharides), and MOS used in human food and dietary supplements.
Scope of the Study
This study analyses the Global Mannan Oligosaccharides Market in terms of value (USD Million) across the segmentations, regions and countries listed below.
Research Objectives
To estimate and forecast the size of the global mannan oligosaccharides market in value terms (USD Million) for 2022–2032.
To analyse the market by livestock (Poultry, Swine, Aquaculture & Others) and by physical form (Powder, Others), identifying the largest and fastest-growing segments.
To assess the market across North America, Europe, Asia Pacific, Latin America and the Middle East & Africa, and across the key countries within each region.
To examine the drivers, restraints, opportunities, trends and challenges affecting MOS adoption, including antimicrobial-use regulations and changes in livestock and aquaculture production.
To evaluate the value chain, from yeast and plant mannan sources through manufacturing and distribution to feed mills, integrators and farmers.
To review the regulatory framework for feed additives and antimicrobial use in major regions and its implications for MOS demand.
To profile the competitive environment, positioning leading suppliers of MOS and yeast cell wall products and tracking their developments since 2022.
To identify growth opportunities in aquaculture, emerging livestock markets and higher-value product formats.
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View Subscription PlansOverview of the Research Process
The study follows a structured process. It starts with defining the market and its segmentation, continues with extensive secondary research and primary interviews, and ends with market size estimation, data triangulation and forecasting. Each stage is reviewed for internal consistency so that segment, regional and country estimates reconcile with the global total for every year from 2022 to 2032.
The process covers five stages: (1) market definition and scoping; (2) secondary research to build a fact base on animal production, feed output, additive usage and supplier activity; (3) primary research with industry participants to validate assumptions and fill data gaps; (4) market sizing using top-down and bottom-up approaches, reconciled through triangulation; and (5) forecasting based on demand-side and supply-side factors, followed by analyst review.
Secondary Research
Secondary research was used to gather data on livestock and aquaculture production, compound feed output, feed additive regulation and supplier activity. The main source types were:
Intergovernmental and government bodies: FAO (FAOSTAT and The State of World Fisheries and Aquaculture), USDA Foreign Agricultural Service, OECD-FAO Agricultural Outlook, Eurostat, national agriculture ministries (such as China’s Ministry of Agriculture and Rural Affairs, India’s Department of Animal Husbandry and Dairying and Brazil’s Ministry of Agriculture and Livestock) and WOAH reports on antimicrobial use in animals.
Regulatory authorities: the European Commission’s EU Register of Feed Additives, EFSA FEEDAP Panel opinions, the U.S. FDA Center for Veterinary Medicine and the Canadian Food Inspection Agency.
Industry associations: the International Feed Industry Federation (IFIF), FEFAC (European Feed Manufacturers’ Federation), FEFANA (EU Association of Specialty Feed Ingredients and their Mixtures), the American Feed Industry Association (AFIA) and national poultry, swine and aquaculture associations.
Company sources: annual reports, investor presentations, regulatory filings, press releases and product literature of yeast, fermentation and feed additive companies.
Trade and scientific literature: feed industry journals and peer-reviewed studies on MOS and yeast cell wall supplementation in poultry, swine and aquaculture.
Paid databases: trade statistics, company financial databases and feed production surveys.
Primary Research
Primary research was conducted through in-depth telephone and online interviews with participants across the value chain. Its objectives were to validate the market definition and segmentation, confirm usage patterns and inclusion rates by species, test pricing and volume assumptions, understand purchasing behaviour, and obtain views on future demand and regulation.
Supply-side respondents included product managers, technical sales managers and business development executives at MOS and yeast cell wall manufacturers, yeast producers, premix companies and distributors. Demand-side respondents included nutritionists and procurement managers at compound feed mills and aquafeed producers, technical managers at integrated poultry and swine companies, veterinarians and farm managers, and pet food formulators. Interviews were spread across the regions covered in the study.
Market Size Estimation
Top-down approach: The global feed additive market and the prebiotic and yeast-derivative sub-category were used as the starting point. The share attributable to MOS and MOS-rich yeast cell wall products was then estimated and allocated across livestock categories, physical forms, regions and countries using production statistics, adoption rates and interview inputs.
Bottom-up approach: Compound feed production by species and country was combined with estimated MOS penetration (the share of feed containing MOS), typical inclusion rates per tonne of feed and average selling prices to calculate consumption value. Country estimates were aggregated to regional and global totals. Supplier revenue estimates for MOS and yeast cell wall products were used as a cross-check.
Data triangulation: Results from the two approaches were compared with supply-side estimates. Differences were resolved through additional primary interviews and analyst judgement, and the final estimates were reconciled so that segment, regional and country values sum to the global total.
Forecasting Methodology
Forecasts were developed by projecting the key demand variables (feed production by species, MOS penetration, inclusion rates and prices) for each country and segment. The factors considered include growth in poultry, swine and aquaculture output; regulatory restrictions on antimicrobial and zinc oxide use; adoption of antibiotic-free production programmes; feed cost trends; disease outbreaks; supply of yeast and yeast co-products; competition from alternative additives; and product innovation in purified and soluble MOS forms.
Historic data (2022–2024) and the base year (2025) were used to calibrate the model. Forecasts for 2026–2032 were then derived using time-series analysis combined with the qualitative impact assessment of drivers and restraints. CAGR values are calculated for the period 2026–2032.
Assumptions and Limitations
All values are expressed in USD Million at nominal prices. Exchange rate fluctuations are not projected separately.
The regulatory environment for antimicrobial use in feed is assumed to remain stable or become stricter during the forecast period, with no reversal of existing bans.
No major global disruption to animal production or feed supply chains, beyond normal cyclical and disease-related variation, is assumed.
Average selling prices of MOS products are assumed to follow moderate trends, reflecting yeast feedstock and energy costs and a gradual shift towards higher-value products.
Private companies do not disclose MOS-specific revenues, so supplier-side estimates rely on interviews and secondary indicators.
Product definitions vary across suppliers (MOS, yeast cell wall, mannan-rich fraction), which introduces some uncertainty in category boundaries.
Base Year
2025
Historical Period
2022 – 2024
Forecast Period
2026 – 2032
Primary Interviews
150+
Historical data (2022–2025) and forecast period (2025–2032)
Our research process spans primary interviews with industry stakeholders combined with comprehensive secondary data analysis, validated through triangulation across multiple independent sources.
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View Subscription PlansIntroduction
The Global Mannan Oligosaccharides Market is moderately consolidated. A small number of global yeast and fermentation specialists account for a large part of branded MOS and yeast cell wall sales, supported by their control of yeast feedstock, processing know-how, trial data and international distribution. Alongside them, a long tail of regional producers, particularly in China, India and Latin America, supply lower-cost products to local feed mills and integrators.
Competition is based on product specification and consistency (guaranteed MOS and beta-glucan content), scientific evidence of efficacy by species, technical service, supply reliability and price. Leading suppliers increasingly offer complete gut-health portfolios combining yeast cell wall products with probiotics, selenium yeast, toxin binders and other yeast derivatives, and position their products within antibiotic-reduction programmes. Since 2022, the industry has seen significant consolidation and capacity investment, including Lesaffre’s acquisition of a 70% stake in Biorigin, Asahi Group Foods’ agreement to acquire Leiber, and expansion of yeast processing capacity by Ohly and Angel Yeast.
Key Player Positioning
The table below lists the companies covered in this assessment, with their latest publicly reported revenue and their relevant MOS and yeast cell wall products. Several companies are privately held or part of larger groups and do not disclose revenue for their animal nutrition or MOS activities.
Leaders
Alltech is one of the pioneers of the MOS category through its Bio-Mos brand and the later Actigen product. Founded in 1980 and privately held, the company operates its largest yeast fermentation plant for animal nutrition in São Pedro do Ivaí, Brazil, which exports to more than 80 countries. Its strategy is vertical integration in yeast production combined with global technical sales. In 2025 Alltech and ADM agreed to combine their North American feed businesses in a joint venture, Akralos Animal Nutrition, which began operating in February 2026, while Alltech retained its specialty ingredients business.
Phileo by Lesaffre is the animal nutrition and health business of the Lesaffre group, one of the world’s largest yeast producers. Its Safmannan yeast fraction is guaranteed for mannan and beta-glucan content. Lesaffre completed the acquisition of a 70% stake in Biorigin, maker of ActiveMOS and MacroGard, in June 2025, and Biorigin is now part of Phileo. The company’s strategy is to use Lesaffre’s fermentation scale for premium, primary-grown yeast fractions and to broaden its scope through acquisitions and new segments such as companion animals, aquaculture and insect farming.
Lallemand Animal Nutrition, part of the privately held Canadian group Lallemand Inc., offers yeast cell wall products such as Agrimos and Optiwall with guaranteed MOS and beta-glucan levels, as well as YANG inactivated yeast fractions. It positions these products as postbiotics within a wider microbial portfolio that includes probiotics and silage inoculants, and has a long-term partnership with ICC Brazil for the supply and development of yeast cell wall products.
Angel Yeast, listed on the Shanghai Stock Exchange, is one of the world’s largest yeast producers and a leading supplier of yeast cell wall products in Asia through its YeaMOS range. The company combines cost-competitive, high-volume production in China with overseas plants in Egypt and Russia, and is moving towards higher-value products such as water-soluble MOS and high-purity beta-glucans.
Challengers
ICC Brazil processes yeast from Brazil’s sugarcane ethanol industry into products such as ImmunoWall and Hilyses, which gives it a cost and scale advantage. It exports to more than 70 countries and supports its products with university trials. Ohly, part of ABF Ingredients, supplies the Ohly-GO Wall and Ohly-GO SoluMannan products and is expanding fermentation and drying capacity in Hamburg and North America. Leiber, a German specialist in brewer’s yeast products, offers Biolex MB40 and related products and agreed in 2025 to be acquired by Asahi Group Foods, which aims to grow the business internationally. Arm & Hammer Animal and Food Production, part of Church & Dwight, markets Celmanax, a yeast-based refined functional carbohydrate product, with a focus on pre-harvest Salmonella control in poultry and on dairy and swine applications.
Niche Players
Biochem Zusatzstoffe offers TechnoMos, a yeast cell wall product high in MOS and beta-glucans, as part of a broader portfolio led by organic trace minerals and toxin binders. Numerous regional producers in China, India and Latin America also serve local markets with lower-cost yeast cell wall and MOS products, competing mainly on price and local service.
Competitor Dashboard
The dashboard below rates each company on four parameters based on analyst assessment of publicly available information.
Threat of New Entrants: Medium
The basic processing technology for yeast cell walls is well known, and regional producers in China and India have entered the market.
Established suppliers hold advantages in feedstock access, brand recognition, trial data and technical service networks.
Feed additive registration and documentation requirements in the EU and other markets raise entry costs.
Bargaining Power of Suppliers: Medium
Yeast supply is concentrated among a few large producers, several of which also sell MOS, giving them control over the main input.
Spent yeast from brewing and ethanol is widely available, which limits supplier power for producers using co-products.
Energy and molasses costs affect processing margins but are not controlled by individual suppliers.
Bargaining Power of Buyers: High
Large integrators and feed mills buy in volume and can switch between suppliers and alternative additives.
MOS is a non-mandatory additive, so buyers can reduce inclusion when margins are under pressure.
Buyers increasingly demand trial data and guaranteed specifications, strengthening their negotiating position.
Threat of Substitutes: High
Probiotics, organic acids, phytogenics, butyrates, enzymes and other prebiotics target similar gut-health outcomes.
Purified beta-glucans and whole yeast products overlap with MOS in some applications.
Substitutes are often combined with MOS rather than replacing it fully, which moderates the threat.
Competitive Rivalry: High
Several global yeast specialists compete with many regional producers on price, specification and service.
Product differentiation is limited for standard yeast cell wall products, leading to price competition.
Consolidation and capacity investment are increasing scale among the leading players.
Threat of New Entrants: Medium.
Bargaining Power of Suppliers: Medium.
Bargaining Power of Buyers: High.
Threat of Substitutes: High.
Competitive Rivalry: High.
Market estimates by geography (2032)
InsightAsia Pacific leads with $64.87M by 2032, while Middle East & Africa is projected to grow fastest at a 6.2% CAGR.
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View Subscription Plans| REGION | 2022 | 2025 | 2032 | CAGR | SHARE |
|---|---|---|---|---|---|
| North America | $25.83M | $31.73M | $38.69M | 4.1% | 21% |
| Europe | $32.97M | $40.19M | $47.90M | 3.8% | 26% |
| Asia Pacific | $35.77M | $47.88M | $64.87M | 6.1% | 35% |
| Latin America | $14.60M | $19.38M | $26.02M | 5.9% | 14% |
| Middle East & Africa | $5.51M | $7.50M | $10.03M | 6.2% | 5% |
| Total | $114.69M | $146.68M | $187.51M | 5.0% | 100% |
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View Subscription PlansTotal Market Size
$187.51M
| APPLICATION | REVENUE ($B) | GROWTH RATE | MARKET PENETRATION |
|---|---|---|---|
| Poultry | $85.15M | 5.2% | 45% |
| Swine | $52.98M | 4.1% | 28% |
| Aquaculture & Others | $49.39M | 5.9% | 26% |
* Revenue projections based on 2025 estimates. Growth rates represent CAGR 2024–2030. Market penetration indicates current adoption rate within addressable market segments.
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Analytical insights on Mannan Oligosaccharides Market covering market dynamics, competitive landscape, and strategic outlook.
The Mannan Oligosaccharides Market market is projected to reach $187.51M by 2032, growing at 5.0% CAGR. The Poultry segment holds the largest share.
The Global Mannan Oligosaccharides Market is shaped by regulation of antimicrobial use, the structure and growth of animal protein production, feed economics and the competitive set of gut-health solutions. This chapter assesses the factors expected to influence demand during 2026–2032. The growth factor table in Section 4.2 summarises five macro and five micro factors with their expected impact. The impact scores (on a scale of 1 to 10) are analyst assessments based on secondary research and industry interviews, and indicate the relative strength of each factor in each period.
Restrictions on Antibiotic Growth Promoters and Antimicrobial Stewardship
The most important long-term driver for MOS is the removal of antibiotics from routine use in feed. The European Union banned antibiotics as growth promoters from 1 January 2006, and Regulation (EU) 2019/6 on veterinary medicinal products, applicable since January 2022, further restricts preventive use of antimicrobials in groups of animals. The EU Farm to Fork Strategy also sets a target of halving sales of antimicrobials for farmed animals and aquaculture by 2030. In the United States, FDA Guidance for Industry #213 ended the use of medically important antimicrobials for growth promotion in 2017 and brought therapeutic feed uses under veterinary oversight through the Veterinary Feed Directive. China banned growth-promoting antibiotics in feed from July 2020 under Ministry of Agriculture and Rural Affairs Announcement No. 194, and India prohibited colistin for food-producing animals and feed supplements in 2019. As producers remove these tools, they rely more on non-antibiotic solutions to maintain gut health and performance, and MOS is among the most established options, with a long record of commercial use and published trials.
Growth and Intensification of Poultry Production
Poultry is the largest consumer of MOS, accounting for USD 59.82 million in 2025. The OECD-FAO Agricultural Outlook identifies poultry as the main source of growth in global meat consumption, driven by its low cost, short production cycle, efficient feed conversion and broad cultural acceptance. Production is shifting from backyard and small-scale systems to integrated, high-density operations in Asia, Latin America, Africa and the Middle East. In these systems, enteric challenges such as necrotic enteritis, coccidiosis-related dysbacteriosis and Salmonella colonisation have a direct effect on margins. Integrators therefore use MOS as part of gut-health programmes for broilers, breeders and layers, often in combination with probiotics, organic acids or phytogenics. Antibiotic-free and “raised without antibiotics” programmes in North America and Europe, and export requirements for poultry from Brazil and Thailand, add to this demand. As a result, poultry is expected to remain the largest segment throughout the forecast period, reaching USD 85.15 million by 2032.
Expansion of Aquaculture
Aquaculture is the fastest-growing source of animal protein. According to FAO’s The State of World Fisheries and Aquaculture 2024, aquaculture overtook capture fisheries in the production of aquatic animals for the first time in 2022. Intensive shrimp, salmon, tilapia and catfish farming faces frequent bacterial and viral disease pressure, including vibriosis, acute hepatopancreatic necrosis disease and white spot syndrome in shrimp, while antibiotic use in aquaculture is under growing scrutiny from importing markets. MOS and yeast cell wall products are used in aquafeeds to support gut integrity, immune response and survival rates. Growth in Asia Pacific (China, India, Vietnam, Indonesia), Latin America (Ecuador, Chile, Brazil) and parts of Africa is expanding the aquafeed base. This is reflected in the Aquaculture & Others segment, which is expected to grow at a CAGR of 5.78%, the fastest of all livestock segments.
Focus on Gut Health, Feed Efficiency and Food Safety
Feed accounts for the largest share of production costs in poultry, swine and aquaculture, so even small improvements in feed conversion have a significant financial effect. Producers increasingly manage gut health as a system, using additives that support a stable microbiota and intestinal integrity. MOS also contributes to pre-harvest food safety programmes by reducing pathogen attachment, which is relevant to Salmonella control obligations such as the EU’s Regulation (EC) No 2160/2003 on the control of Salmonella and other specified food-borne zoonotic agents. In swine, the EU prohibition on veterinary medicines containing high doses of zinc oxide, effective from June 2022, increased demand for alternative solutions to support piglets after weaning, including yeast cell wall products. Supplier investment in species-specific trials and technical service has helped integrators measure returns on MOS use, which supports wider adoption.
Aquaculture and Shrimp Farming in Asia and Latin America
Shrimp and fish farming in China, India, Southeast Asia, Ecuador and Chile offers a large and under-penetrated market. Aquafeed producers are looking for functional ingredients that improve survival and disease resistance without antibiotics. Suppliers that offer species-specific products, pellet-stable forms and trial data under local conditions can build strong positions in this segment.
Purified, Soluble and Combination Products
The development of purified MOS fractions, water-soluble products for drinking-water application and synbiotic combinations with probiotics or other active ingredients allows suppliers to differentiate on performance and move away from commodity pricing. The Others physical form segment, which includes such formats, is expected to grow at a CAGR of 6.81%, ahead of the Powder segment.
Emerging Livestock Markets
Commercial poultry, swine and aquaculture production is expanding rapidly in India, Southeast Asia, Africa and the Middle East, where governments are also introducing stricter rules on antimicrobial use. As production becomes more organised and integrated, adoption of feed additives such as MOS typically rises. Local manufacturing, distribution partnerships and technical training for feed mills are key to capturing this demand.
Variable Composition and Inconsistent Efficacy
MOS products vary in yeast strain, source (primary-grown versus brewery or ethanol co-product), processing method and the resulting levels of mannan, beta-glucan and protein. Published trials show positive results in many cases, but responses differ with the level of disease challenge, diet composition, animal age and farm management. This variability makes some nutritionists cautious, particularly when returns are hard to demonstrate under good hygiene conditions. Lower-priced products with unclear specifications add to the problem and can damage confidence in the category.
Price Sensitivity and Feed Cost Pressure
Feed additives are usually among the first costs that producers review when grain and protein meal prices rise or animal prices fall. MOS is a non-mandatory additive, so its inclusion competes with other spending priorities. In price-sensitive markets with fragmented, small-scale producers, the cost per tonne of feed can limit penetration, and large integrators and feed mills use their purchasing power to negotiate prices down.
Competition from Alternative Gut-Health Additives
MOS competes with a wide range of solutions aimed at the same outcomes, including probiotics (Bacillus, Lactobacillus and yeast strains), organic acids, medium-chain fatty acids, butyrates, phytogenics and essential oils, enzymes and other prebiotics such as fructo- and xylo-oligosaccharides. Many of these have strong scientific support and active marketing, and buyers often select combinations based on cost and local experience, which limits the share available to MOS in some feed programmes.
Upcycling of Yeast Co-Products
Suppliers are increasingly sourcing yeast cell wall material from brewing and sugarcane ethanol fermentation, turning co-products into higher-value feed ingredients. Companies such as ICC Brazil, Biorigin and Leiber build their business models on this approach, which offers cost and sustainability benefits but requires strict quality control to deliver consistent products.
Industry Consolidation
Consolidation is reshaping the supply base. Lesaffre completed the acquisition of a 70% stake in Biorigin in 2025 and has since brought it under Phileo by Lesaffre, while Asahi Group Foods agreed in March 2025 to acquire Leiber. Large yeast groups are using acquisitions to secure feedstock, add products and expand geographically.
Positioning of Yeast Fractions as Postbiotics
Suppliers increasingly market yeast cell wall products and other inactivated yeast fractions as postbiotics, alongside probiotics and prebiotics. This positioning supports integrated gut-health programmes and helps differentiate higher-value products, although terminology and claims vary between markets.
Challenge: Disease Outbreaks and Market Volatility
Outbreaks of African swine fever in Asia and Europe and of highly pathogenic avian influenza in many regions have caused large losses of animals and sudden shifts in production and trade. These events disrupt demand for feed additives in affected markets and make forecasting difficult, even though they also increase interest in biosecurity and animal health solutions.
The MOS value chain links yeast and plant mannan sources with feed mills, integrators and farmers. The main stages are described below.
Raw materials: Access to consistent yeast feedstock is a key source of advantage. Large yeast producers (Lesaffre, Lallemand, Angel Yeast) can supply primary-grown yeast, while companies in Brazil benefit from abundant ethanol-plant yeast. Brewery yeast is widely available in Europe and North America but varies more in composition.
Manufacturing: Value is created by processing technology that controls the release and purity of the cell wall fraction, and by drying and standardisation. Higher-purity and soluble products require more processing and command higher prices.
Distribution: Technical sales and trial support are central, as buyers want evidence of performance under their own conditions. In many emerging markets, distributors and premixers provide local reach and formulation support.
End users: Integrators and large feed mills make most purchasing decisions, based on cost per tonne of feed, documented efficacy and supply reliability.
MOS is regulated as a feed ingredient or feed additive depending on the jurisdiction and the claims made. Demand is also strongly influenced by rules on antimicrobial use in food-producing animals. The key regulations by region are summarised below.
Jul 2022: Biochem Zusatzstoffe; Expansion; Opened a new 4,500 m² GMP+ production and logistics plant in Lohne, Germany, including tank storage and automated filling for liquid feed additives.
Dec 2022: Angel Yeast; Expansion; Started a 20,000 tonnes per year yeast capacity expansion at its plant in Egypt, raising site capacity to 60,000 tonnes per year.
Jun 2023: Phileo by Lesaffre; Expansion; Opened a new factory in Valladolid, Spain, producing Selsaf selenium-enriched yeast.
Sep 2023: Leiber GmbH; Expansion; Announced its first U.S. operation in Rockingham County, Virginia, with an investment of up to USD 20 million.
Oct 2023: Lallemand Animal Nutrition; Launch; Launched the LALPROBIOME brand of yeast- and bacteria-based prebiotics and postbiotics for pets.
2024: Arm & Hammer Animal and Food Production; Launch; Introduced Celmanax Ultra, a concentrated yeast-based product for broilers, layers and turkeys used at half the inclusion rate of Celmanax.
May 2024: Lallemand Animal Nutrition; Investment; Invested in energy and resilience upgrades at its selenium-enriched yeast plant in Felixstowe, U.K.
Oct 2024: Ohly (ABF Ingredients); Expansion; Announced a new spray-drying tower and fermentation plant in Hamburg, adding up to 50% capacity.
Oct 2024: Lesaffre / Biorigin; Acquisition; Announced an agreement to acquire a 70% stake in Biorigin from Zilor, forming a yeast derivatives joint venture.
Nov 2024: Angel Yeast; Launch; Introduced YeaMOS S, a water-soluble yeast cell wall product with concentrated mannan oligosaccharides.
Feb 2025: Arm & Hammer Animal and Food Production; Launch; Presented BG MAX at IPPE 2025 as a new-generation solution targeting Enterococcus, Salmonella and E. coli.
Mar 2025: Leiber GmbH / Asahi Group Foods; Acquisition; Asahi Group Foods agreed to acquire 100% of Leiber to combine yeast cultivation technology with Leiber’s yeast extract and yeast cell wall expertise.
Jun 2025: Lesaffre / Biorigin; Acquisition; Completed the acquisition of a 70% stake in Biorigin, with Zilor retaining 30%.
Jul 2025: Phileo by Lesaffre; Investment; Made a strategic investment in CanBiocin to offer probiotic solutions for companion animals through Phileo.
Sep 2025: Alltech; Partnership; Agreed with ADM to form a North American animal feed joint venture majority-owned by Alltech.
Oct 2025: Angel Yeast; Expansion; Announced the third stage of its plant in Lipetsk, Russia, with 22,000 tonnes per year of additional capacity.
Feb 2026: Alltech; Partnership; Akralos Animal Nutrition, the Alltech–ADM feed joint venture, began operations with more than 40 feed mills.
May 2026: Ohly (ABF Ingredients); Expansion; Announced plans for a new Ohly North American campus in Eau Claire, Wisconsin, with a first phase investment of more than USD 65 million.
Jul 2026: Phileo by Lesaffre / Biorigin; Integration; Biorigin announced that it is now part of Phileo by Lesaffre.
Jul 2026: Lallemand; Acquisition; Completed the acquisition of BIO-CAT, expanding its U.S. footprint and production capacity.
Sep 2026: Lallemand Animal Nutrition; Partnership; Entered the SCAN research partnership with CCPA Group and IRSET on livestock nutrition and immunity.
Political
National action plans on antimicrobial resistance, aligned with the WHO, FAO and WOAH One Health approach, are reducing antimicrobial use in livestock.
Food security policies in the Middle East, Africa and Asia support domestic poultry and aquaculture production.
Trade policies and sanitary requirements of importing countries influence production practices in exporting nations such as Brazil and Thailand.
Economic
Feed grain and protein meal price volatility affects producers’ willingness to spend on additives.
Rising incomes in emerging economies increase demand for poultry, pork and seafood.
Currency movements affect the cost of imported additives in markets such as Argentina, Egypt and Türkiye.
Social
Consumer demand for meat and fish produced without antibiotics is growing, particularly in North America and Europe.
Animal welfare expectations encourage practices that support animal health and reduce mortality.
Urbanisation is shifting diets towards affordable animal protein, especially poultry.
Technological
Improved fractionation and enzymatic processes allow higher-purity and soluble MOS products.
Advances in microbiome research help quantify the effects of MOS on gut microbiota and immunity.
Combination products with probiotics and other actives are expanding formulation options.
Environmental
Upcycling of spent yeast from brewing and ethanol supports circular economy goals.
Better feed efficiency reduces resource use and emissions per unit of animal protein.
Climate-related disease and heat stress increase the need for gut-health and immunity support.
Legal
Feed additive authorisation and labelling rules differ between jurisdictions, affecting time to market.
Restrictions on health claims limit how MOS products can be marketed in some regions.
Bans and restrictions on antimicrobials and high-dose zinc oxide create demand for alternatives.
Profiles of 107 companies operating in the Mannan Oligosaccharides Market market, including revenue, employee count, and market positioning where available.
Showing 107 of 107 companies
3 interactive charts drawn from the Mannan Oligosaccharides Market dataset — market size, regional splits and each segment breakdown. Open one to read its full data table and download it.
Global Mannan Oligosaccharides Market By Physical Form
Global Mannan Oligosaccharides Market By Livestock
Global Mannan Oligosaccharides Market By Region
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Historical performance and future projections (2020–2030, USD Billion)
Market Size (USD Million)
