Company ProfilePremiumNov 11, 2026

PRINCIPIA BIOPHARMA

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PRINCIPIA BIOPHARMA - Healthcare showcase

Year Founded & Workforce

2008

57 Employees

Industry

Healthcare

Services

Pemphigus Vulgaris

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PRINCIPIA BIOPHARMA Overview

Company Headquarters: South San Francisco, CA (US)

Founded: 2008

Workforce: ~57

Company Working: Principia Biopharma (Principia) functions as a late-stage biopharmaceutical company focused on developing novel therapies for serious immune mediated diseases. The company offers and develops drugs for the treatment of cancer. The company serves the US market.

Principia Biopharma patented tailored covalency platform allows to develop and design small covalent molecules.

Strategy

Pricipia Biopharma has orphan drug designation for its molecules coupled with strong collaborations to develop drugs through clinical trials. The positive cash flows in the past year has helped the company to continue the drugs for phase 3 clinical trials. If approved, the company has options to gain revenues through commercialization, licensing, and/or royalties for its patented drugs.

Company Snapshot

Employees

2008

Founded

South San Francisco, CA (US)

Headquarters

SWOT Analysis

Strengths

Strong clinical pipeline
Tailored covalency platform for reproducibility
Collaboration for drug development
Positive cash flows

Weaknesses

Major revenue dependence on the upfront payment from collaboration

Opportunities

Utility of available molecules for other indications
Development and commercialization of drugs

Threats

Revenues are subject to clinical trial results

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Key Developments

Date	Approach	Development
January 2020	Product Development	Principia announced the expansion of its BTK franchise with PRN473 Topical. Principia believes topical administration will be an important addition to the expected utility of systemic BTK inhibition (rilzabrutinib) and CNS-penetrant BTK therapy (SAR442168/PRN2246).
December 2019	Product Development	Principia updated the PRN1008 Pemphigus clinical program with accelerated enrollment of company’s Phase 3 pivotal trial anticipating results by second half of 2021.

Product Offering

PRINCIPIA BIOPHARMA
- Pemphigus Vulgaris

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About the Author

Wantstats Research Team

Wantstats' research desk profiles PRINCIPIA BIOPHARMA as part of our ongoing coverage of the Healthcare sector, drawing on public company data, filings, and market intelligence.

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