Market Size (2018)
2018
$10.80B
Vertical: HealthcareBase Year: 202112 Sections
Market Size (2018)
2018
$10.80B
Projected (2030)
2030
$19.96B
CAGR (2018–2030)
5.2%
5.2%Key Players
108+
Dercum’s disease is a rare disorder described by multiple, painful growths of fatty tissue (lipomas). The key factors attributing to driving the market growth are the rising prevalence of rare diseases. However, the lack of awareness among people about the disease is a threat to the growth of the market. In contrast, a rising number of strategic initiatives is likely to create market opportunities for global market leaders.
The Dercum’s Disease Market market is projected to grow at a CAGR of 5.2% from 2018 to 2030.
Historical performance and future projections (2020–2030, USD Billion)
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View Subscription PlansDercum’s disease is a rare disorder that affects painful growths of fatty tissue called lipomas. Fat tissue is known as loose connective tissue, hence Dercum’s disease is a loose connective tissue disease. The lipomas mainly occur on the trunk, the upper arms, and upper legs and are found just below the skin but also can be found deeper in the body coupled to muscle, tendons, ligaments, or bone by connective tissue. Pain associated with Dercum’s disease can often be severe.
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View Subscription PlansThis report applies a rigorous multi-stage research process combining primary interviews, secondary data sources, and bottom-up market modelling to ensure accuracy and completeness across all segments and geographies.
Base Year
2021
Historical Period
2018 – 2021
Forecast Period
2021 – 2030
Primary Interviews
150+
Historical data (2018–2021) and forecast period (2021–2030)
Our research process spans primary interviews with industry stakeholders combined with comprehensive secondary data analysis, validated through triangulation across multiple independent sources.
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View Subscription PlansThreat of New Entrants
The threat of new entrants in the global Dercum’s disease market is low. Any manufacturing company trying to enter the market is required to accept and abide by the mandatory regulatory standards set by the respective regulatory authorities of the country, such as the Food and Drug Administration (FDA), The Central Drugs Standard Control Organization (CDSCO), and others. Moreover, the market is also characterized by a reasonable degree of brand loyalty, where establishing a brand name is difficult for newcomers. Furthermore, the cost involved in the R&D of a product is comparatively high, which does not allow new players to enter the market easily.
Bargaining Power of Suppliers
The bargaining power of suppliers in the global Dercum’s disease market is moderate. The suppliers in the Dercum’s disease market are the developers and manufacturers of devices used for treating Dercum’s. The bargaining power of suppliers is a crucial factor in the global Dercum’s disease market and determines the strength of the industry. Many suppliers are currently present in the market due to the availability of a huge patient pool, high demand for Dercum’s treatment, and increasing government support. The existing key companies capture significant market share and monitor the costs of the devices. The switching cost of these suppliers is moderate because suppliers tend to enter long-term associations, partnerships, and deals with other manufacturing companies. The overall bargaining power of suppliers in the global Dercum’s disease market is hence moderate.
Threat of Substitutes
The threat of substitutes in the global Dercum’s disease market is low. Patients suffering from Dercum’s disease have surgical, medication, liposuction, electrotherapy, acupuncture treatment options that show promising results. Furthermore, many large- and medium-scale companies manufacture different types of devices and medications for Dercum’s treatment. Some small companies are providing their products at low prices to sustain themselves in this highly competitive market.
Bargaining Power of Buyers
The bargaining power of buyers is high in the global Dercum’s disease market. This is primarily due to the presence of a growing number of buyers in the industry. The market for Dercum’s disease is identified as having a significant customer base, considering the increasing number of rare diseases, and rising research and development activities. However, the buyers tend to use the products that have been provided by the top players irrespective of the pricing. Therefore, the bargaining power of buyers is high in the global Dercum’s disease market.
Intensity of Rivalry
The overall degree of competition in the global Dercum’s disease market is high. The number of competitors is high and offers a wide variety of products for Dercum’s disease. The reserved degree of product differentiation among existing players increases the intensity of rivalry in the market. The companies engaged in manufacturing drugs and treatments are developing advanced products for differentiating their brand from the competitors. Also, many prominent market players are entering into strategic partnerships, co-development activities, and tie-ups with established companies to overcome the competition.
Market estimates by geography (2030)
InsightEurope leads with $7.66B by 2030, while Asia Pacific is projected to grow fastest at a 5.8% CAGR.
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View Subscription Plans| REGION | 2018 | 2021 | 2030 | CAGR | SHARE |
|---|---|---|---|---|---|
| North America | $3.71B | $4.52B | $6.84B | 5.2% | 34% |
| Europe | $4.30B | $5.25B | $7.66B | 4.9% | 38% |
| Asia Pacific | $2.13B | $2.60B | $4.18B | 5.8% | 21% |
| Rest of the World | $656.95M | $801.47M | $1.27B | 5.6% | 6% |
| Total | $10.80B | $13.18B | $19.96B | 5.2% | 100% |
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View Subscription PlansTotal Market Size
$19.96B
| APPLICATION | REVENUE ($B) | GROWTH RATE | MARKET PENETRATION |
|---|---|---|---|
| Surgery | $6.22B | 5.2% | 72% |
| Liposuction | $4.95B | 5.2% | 89% |
| Medication | $4.14B | 5.2% | 67% |
| Electrotherapy | $2.12B | 5.2% | 89% |
| Acupuncture | $1.85B | 5.2% | 89% |
| Others | $686.47M | 5.2% | 53% |
* Revenue projections based on 2025 estimates. Growth rates represent CAGR 2024–2030. Market penetration indicates current adoption rate within addressable market segments.
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Analytical insights on Dercum’s Disease Market covering market dynamics, competitive landscape, and strategic outlook.
The Dercum’s Disease Market market is projected to reach $19.96B by 2030, growing at 5.2% CAGR. The Surgery segment holds the largest share.
Dercum’s disease is a combination of chronic painful adipose tissue. Treatment for this disease is centered on managing pain. Although there is no standard of care for managing pain, there are different pain management regimes that are promising. The key factors driving the global Dercum’s disease market growth include the rising prevalence of rare diseases and increasing research and development activities. Additionally, the rising number of strategic initiatives will provide growth opportunities for the market in the future. However, a lack of awareness among people about the disease might hamper the market's growth in the forecast period.
The increasing prevalence of rare diseases is propelling the demand for effective treatment for Dercum’s disease. Rare diseases such as adiposis dolorosa, and lipomas along with the ongoing COVID-19 pandemic, account for a substantial burden globally. According to the NCBI survey, held in February 2021, approximately 2500 people per year with loose connective (adipose) tissue disease were seen, most patients with lipedema, six patients with FML-Type DD, and 10 patients with angiolipoma-type Dercum’s disease. Additionally, the same survey suggested that the prevalence of Dercum’s disease is 0.64% in the population, and the prevalence of lipedema in the USA is thought to be 11% in women though the range is 5 to 39%. A majority of people with Dercum’s disease are women.
Dercum's disease is characterized by multiple, painful growths of fatty tissue (lipomas). So, the number of patients suffering from rare diseases increasing globally. Moreover, the increasing cases of COVID-19 also have a significant impact on the growth of the Dercum’s disease market. Such rise in the number of diseases cases is anticipated to augment the demand for Dercum’s disease globally.
Dercum’s disease is a rare condition that is characterized by multiple, painful fatty tumors that occur chiefly in post-menopausal, obese women of middle age. It is also known as Adiposis Dolorosa, Anders' syndrome, and Dercum-Vitaut syndrome. Therefore, rise in the number of strategic initiatives in the form of mergers, acquisitions, product approval, collaborations, and partnerships to gain a competitive edge and offer advanced treatment options for Dercum’s disease. For instance, in August 2019, BioSpecifics Technologies Corporation, a biopharmaceutical company that originated and continues to develop collagenase based-therapies with a first-in-class collagenase-based product collagenase clostridium histolyticum, or CCH, marketed as XIAFLEX in the US and Xiapex in Europe.
Similarly, in August 2022, Caliway Biopharmaceutical Inc (CBI) announced that its first pipeline, CBL-514 has demonstrated promising clinical effectiveness and safety in reducing local fat through a mechanism of adipocyte apoptosis. Hence, such initiatives will help to propel the Dercum’s disease market.
The lack of awareness regarding symptoms, ignorance, and not seeking timely diagnosis and treatment for Dercum’s disease is anticipated to hamper the market growth. The National Center for Biotechnology Information (NCBI) in February 2021, stated that less than 200,000 people globally suffer from Dercum’s disease. However, half of them could have been prevented by receiving proper treatment on time. The lack is awareness is more in the developing regions of the world where people are not conditioned to understand the therapeutic approach beyond the need.
According to the National Library of Medicine article published in December 2019, Dercum’s disease is more prevalent in women than in men, with increasing age, and in some ethnic groups. The study also stated that a significant proportion of the population suffering from Dercum’s did not receive proper treatment. As many got risk factors exist, including obesity, dietary factors, and comorbid conditions. Therefore, a lack of awareness regarding Dercum’s negatively impacts the growth of the Dercum’s disease market. However, several efforts are being undertaken by regulatory authorities in the form of campaigns and awareness programs to improve public awareness, which is expected to decrease the impact of restraints in the coming years.
The novel coronavirus or the COVID-19 pandemic has negatively impacted the global Dercum’s disease industry since the rising number of decrum's disease cases have been affected since the healthcare service providers and frontline workers are focused more on handling the upcoming covid cases have reduced the significant consideration being paid to the decorum’s disease. Several countries have also implemented certain restrictions on imports and exports because of the pandemic. This has also affected the healthcare industry as many countries are dependent on other countries for raw material supply, component supply, system supply, and technology. This has also impacted the market as patients and staff need to work in proximity regularly. Furthermore, due to the closure of the operational facility, hospital and clinics were having a difficult time. Similarly, during the pandemic, 62% of healthcare professionals in the US had salary concerns. However, as the restrictions are lifted as COVID-19 cases decreases, treatment will be available in different parts of the world, and the trade restrictions are lifted, the supply chain should return to normalcy soon.
The emergence of coronavirus negatively impacted various sectors across the globe. The healthcare sector was also negatively impacted owing to production restrictions, cessation of clinical trials, and R&D activities. However, increasing number of techniques to confirm the presence or absence of coronavirus among patients is creating huge demand globally. The sudden surge in rare diseases has created a pressure among the market players to produce medication. In addition, the rising number of patients is driving the demand for decrum's disease treatment option. The commercialization of the products has also strengthened the market demand. Thus, these factors augmented the demand for decrum's disease treatment across worldwide.
The COVID-19 pandemic situation has resulted in many restrictions globally, still players of decrum's disease market were able to manage their product stock globally. Companies are trying to deal globally also finding out their way to deal with this pandemic situation. They are experiencing volatile demand flow, fluctuating by regions and market sectors. Hence, they are in regular contact with government authorities to maintain the product supply across the border. The outbreak of COVID-19 and the subsequent measures implemented by the government to contain it have badly affected the suppliers. Furthermore, Asia Pacific countries such as China, Japan, and India are also badly affected due to the pandemic. The demand-supply outlook is severely hampered by trade barriers. Government and private companies in the regions are also working together to issue advice for those undergoing treatment during these unprecedented times of COVID-19.
Profiles of 108 companies operating in the Dercum’s Disease Market market, including revenue, employee count, and market positioning where available.
Showing 108 of 108 companies
Novartis International AG
Company Headquarters: Basel, Switzerland Founded: 1966 Workforce: ~108,000 Company Working: Novartis International AG (Novartis) is engaged in the production of pharmaceutical drugs. It is a fully integrated life sciences company that provides research, product development, manufacturing, and distribution of products. It is an outstanding worldwide source of regenerative medicine technology, clinical research, education, and training for the constantly evolving healthcare industry. It ranks among the world’s top companies investing in research and development. It carries out research at Novartis locations and partner institutions worldwide: Cambridge, the US; Basel, Switzerland; East Hanover, US; Emeryville, US; and Shanghai, China. Sandoz, a Novartis division, is a global provider of generic pharmaceuticals and biosimilars.
BHR Pharmaceuticals Ltd
Company Headquarters: England, UK Founded: 1990 Workforce: ~50 Company Working: BHR Pharmaceuticals Ltd is a fastest growing point of care diagnostic company which is involved in development medical devices. The company specialize in hematology, health equipment, immunology, point of care testing equipment, allergy testing supplies, migraine device, drug tests, and female health. Moreover, the company offers most technically advanced products and solutions to diagnose and treat as well as manage most prevalent diseases. The company has strong business presence in UK.
Raziel Therapeutics Ltd
Company Headquarters: Hamerkaz, Israel Founded: 2012 Workforce: ~10 Company Working: Raziel Therapeutics Ltd is a clinical-stage pharmaceutical company which is developing injectable therapeutics for the treatment of aesthetics and a variety of fat disorders. The company provide a single injection treatment into subcutaneous fat which is cause fast fat cell death at injection site as well as empowering medical professionals to enable patients with a better treatment fat reduction for long time periods without noninvasive procedure. The company has strong business presence in Israel.
Caliway
Company Headquarters: New Taipei City, Taiwan Founded: 2012 Workforce: <25 Company Working: Caliway is a clinical stage biopharmaceutical company which is involved in development of innovative therapeutics in the treatment of obesity and anti-aging disorders. The company developing small molecule for non-surgical fat reduction, Dercum’s disease, cellulite, lipoma, osteoarthritis, and others. Moreover, the company pipeline molecule CBL-514, is a first-in-class new drug which can activate adipocyte apoptosis at the injection site and efficiently reduce the subcutaneous fat without any serious side effects. The company has strong business presence in Taiwan.
Pfizer Inc.
Company Headquarters: New York, US Founded: 1849 Workforce: ~83,000 Company Working: Pfizer Inc. (Pfizer) is a leading research-based biopharmaceutical company that applies science and resources to provide innovative treatments that extend and significantly improve lives. Pfizer discovers, develops, manufactures, and sells healthcare products worldwide. It operates through two segments: Pfizer Innovative Health (IH) and Pfizer Essential Health (EH). It also provides sterile injectable pharmaceuticals, biosimilars, active pharmaceutical ingredients (APIs), and contract manufacturing services. Pfizer sells its products through wholesalers, retailers, hospitals, clinics, government agencies, and pharmacies. It has major manufacturing facilities in India, China, Japan, Ireland, Italy, Belgium, Germany, Singapore, and the US. Furthermore, the company supplies its products in North America, South America, Asia-Pacific, Australia, Europe, Africa, and the Middle East.
Abbvie Inc.
Company Overview Company Headquarters: Illinois, US Founded: 2013 Workforce: 30,000+ Company Working: Abbvie Inc. (Abbvie) is a pharmaceutical company that deals in various products addressing a variety of therapeutic areas such as oncology, immunology, neuroscience, virology, and general medicine. The company’s team consists of scientists, researchers, communicators, manufacturing specialists, and regulatory experts all across the globe. Abbvie targets specific difficult-to-cure diseases where it can leverage its core R&D expertise to advance science. It constantly works towards creating solutions that go beyond treating the illness to have a positive impact on patients’ lives and societies. The company comes up with new approaches towards addressing current health issues from life-threatening illness to chronic conditions.
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Dercum’s Disease Market