Market Size (2018)
$20.38B
Vertical: HealthcareBase Year: 201814 Sections
Market Size (2018)
$20.38B
Projected (2024)
$53.42B
CAGR (2016–2024)
16.9%
Key Players
10+
Tissue engineering mainly focuses on the development of tissue and organ substitutes by controlling biological parameters in the laboratory. It helps to elaborate the three-dimensional cellular constructs with properties more like natural tissues. Growing aging patient population, the rise in tissue engineering transplantations globally, and rising disease awareness drive the growth of the global tissue engineering market. However, stringent regulatory policies may hamper the growth of the market.
The global tissue engineering market is expected to register a CAGR of 17.84% during the forecast period from 2019 to 2024. In 2018, the market was led by the Americas with 39.3% share, followed by Europe and Asia-Pacific with shares of 30.4% and 21.4%, respectively.
The global tissue engineering market has been segmented based on material, application, and region.
Based on material, the nano-fibrous material segment accounted for the largest market share of 30.0% in 2018, with a market value of USD 6,117.81 million, which is projected to register a CAGR of 18.08% during the forecast period.
Based on application, the orthopedics, musculoskeletal and spine segment accounted for the largest market share of 33.4% in 2018, with a market value of USD 6,804.75 million, which is projected to register a CAGR of 17.03% during the forecast period.
The Tissue Engineering Market market is projected to grow at a CAGR of 16.9% from 2016 to 2024.
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View Subscription PlansTissue Engineering Market
Historical performance and future projections (2020–2030, USD Billion)
Market Size (USD Mn)
Tissue engineering is designed to influence the physical, chemical, and biological environment surrounding the cell population. It is an interdisciplinary field that applies the principle of engineering and life science towards the development of biological products that help improve the functioning of tissues or a whole organ. Tissue engineering provides solutions that can replace or either repair tissue including transplant, surgical reconstruction, and medical devices. Moreover, increasing awareness regarding the benefit of tissue engineering in individuals as well as healthcare professionals would create more demand for these products. Hence it helps to boost the growth of the global tissue engineering market.
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View Subscription PlansThis report applies a rigorous multi-stage research process combining primary interviews, secondary data sources, and bottom-up market modelling to ensure accuracy and completeness across all segments and geographies.
Base Year
2018
Historical Period
2016 – 2017
Forecast Period
2019 – 2024
Primary Interviews
150+
Historical data (2016–2018) and forecast period (2018–2024)
Our research process spans primary interviews with industry stakeholders combined with comprehensive secondary data analysis, validated through triangulation across multiple independent sources.
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View Subscription PlansThe global tissue engineering market seems to be a very lucrative, attractive, and profitable market, both for existing as well as new entrants. At the same time, intense rivalry among existing competitors has been observed. Our analysis revealed that market players had adopted different strategies to increase their business and position in the global tissue engineering market. In recent years, strategic movements by major players were product launches, acquisitions, and approvals, which have been used as market penetration strategies and to reduce competition. The major players in the global tissue engineering market are Stryker, Zimmer, Medtronics, DePuy Synthes, Baxter, Acelity, Cook Medical and others.
Companies are now entering into acquisitions to neutralize growing competition from customers, competitors, and to tackle the changing market dynamics.
There are numerous players operating in this market all over the globe. Most of these players exist in the American and European regions. There are a lot of large and small market players available in the market which provide a wide range of products for various applications. As there are many large and small players in the market, the market shares of these players are much differentiated. Some of the major players who provide tissue engineering products include Stryker, Allergan, Medtronic, Zimmer, Baxter International, Integra LifeSciences, Organovo Holdings Inc., Cook Medical, DePuy Synthes, Acelity and others.
Stryker, Zimmer, Medtronics, DePuy Synthes, Baxter, Acelity, Cook Medical, are top players in the global tissue engineering market, contributing all most 78.3% of the total global market.
Bargaining Power of Suppliers
The bargaining power of the suppliers estimates how easy it is for the suppliers to influence the prices of the tissue engineering market. The market impact of the supplier’s bargaining power is considered to have a medium level impact. Businesses must obtain the necessary resources that they need from the resource suppliers to carry out their activities. The price of tissue engineering products is determined by the interaction between the suppliers and the end users. The number of suppliers serving the tissue engineering market is high as compared to the number of tissue engineering manufacturing firms operating in the sector, while the competition among the suppliers is high due to the high value of the transaction. Thus, the firms have a strong position due to lower switching cost relative to the suppliers. The factors favoring the suppliers are the high degree of differentiation and high quality of inputs used in the manufacturing of tissue engineering products, which reduces the chances of a reliable and quality supplier being substituted.
Bargaining Power of Buyers
The bargaining power of the buyers assesses how easy it is for the buyers to affect the price of tissue engineering. The bargaining power of the buyer will be low for tissue engineering as the tolerance for substandard products and substitutes is less due to the critical role of the tissue engineering products. The tissue engineering market is a consolidated market with the buyers to firm concentration ratio being low which reduces the power of the buyers. The factors in favor of the buyer are, the rising availability of information to the buyers, increasing penetration of insurance, rising government incentives and reimbursements, and the rising price sensitivity of the buyers.
Threat of New Entrants
Threat from new entrants is low. The tissue engineering market is a specialized market with high growth potential and requiring high technological knowledge. The tissue engineering market is also highly sensitive to technological advancements and disruptive innovations. Development of any novel tissue engineering with even a small advantage over existing products will have a disastrous effect on the existing players. The tissue engineering industry has a high capital and research intensity which raises the bar for market entry with the capital investment in technology being very high. The tissue engineering market also needs highly skilled manpower. The research intensity and higher intellectual property utilized in the industry makes a new technology highly disruptive of existing technology and players.
Threat of Substitutes
The threat of substitutes is medium to high for the tissue engineering market. The threat from the substitutes arises when the customers or the buyers in the market can achieve the end-result using other means excluding the concerned market. Tissue engineering has poor alternatives in the form of synthetic implants. Synthetic implants and artificial products cannot challenge the application of tissue engineering either the huge future potential of tissue engineering. However, if the event of the development of any threat of a substitute it will affect the existing players to a high degree. Thus, product development of these alternatives possesses a significant risk to the tissue engineering market.
Intensity of Rivalry
Degree of competition is considered to have a high impact on the market. The intensity of competitive rivalry evaluates the capability and the level of rivalry among competitors in the market. It also refers to the extent to which firms within a market put pressure on one another and limit each other’s profit potential. Industries strive for a competitive advantage over their rivals, and the intensity or rivalry varies across industries. Rivalry among market players can affect market profits through downward pressure on prices, increased innovation, increased advertising, and increased service/product improvements, among others. So, the intensity of rivalry is high.
Market estimates by geography (2024)
InsightAmericas leads with $20.29B by 2024, while Asia Pacific is projected to grow fastest at a 17.5% CAGR.
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View Subscription Plans| REGION | 2016 | 2018 | 2024 | CAGR | SHARE |
|---|---|---|---|---|---|
| Middle East and Africa | $1.36B | $2.47B | $4.83B | 17.2% | 9% |
| Americas | $6.08B | $10.70B | $20.29B | 16.3% | 38% |
| Asia Pacific | $3.25B | $5.96B | $11.79B | 17.5% | 22% |
| Europe | $4.62B | $8.42B | $16.51B | 17.3% | 31% |
| Total | $15.30B | $27.56B | $53.42B | 16.9% | 100% |
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View Subscription PlansTotal Market Size
$53.42B
| APPLICATION | REVENUE ($B) | GROWTH RATE | MARKET PENETRATION |
|---|---|---|---|
| Nano-fibrous material | $16.24B | 17.2% | 30% |
| Biomimetic material | $12.54B | 17.5% | 23% |
| Composite material | $10.86B | 17.3% | 20% |
| Nano-composite material | $9.56B | 17.0% | 18% |
| Others | $4.24B | 13.7% | 8% |
* Revenue projections based on 2025 estimates. Growth rates represent CAGR 2024–2030. Market penetration indicates current adoption rate within addressable market segments.
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Analytical insights on Tissue Engineering Market covering market dynamics, competitive landscape, and strategic outlook.
The Tissue Engineering Market market is projected to reach $53.42B by 2024, growing at 16.9% CAGR. The Nano-fibrous material segment holds the largest share.
Tissue engineering provides solutions that can replace tissue repair solutions that are currently used. These tissue repair solutions include transplants, surgical reconstruction, and mechanical devices. The growing geriatric population, increasing incidence rate of chronic and infectious diseases, 3D bioprinting emerging as a novel tissue engineering strategy due to its cost efficiency, and increased focus of companies on tissue engineering-based therapies are the factors that are enhancing the market growth of the segment. However, lack of awareness regarding tissue engineering, lack of skilled professionals, and stringent regulatory policies are projected to curb the growth of the market.
Geriatric population, i.e., people above the age of 65 years have low immunity and are more vulnerable towards suffering from various types of disorders. Additionally, along with the lower immune response, aged people are more prone to suffer from chronic wounds as compared to young people. Moreover, they have high chances of transplant rejection. Therefore, cell transplantation, which is a branch of tissue engineering is a prominent solution to tackle such problems. According to the Office for National Statistics in 2017, approximately 18% and 2.4% of the total UK population was aged over 65 years and 85 years, respectively. Hence, increasing geriatric population is positively impacting the growth of the global tissue engineering market.
Developing economies pose an opportunity for various markets as they have undeveloped research and development sectors owing to which they are unable to address upcoming health challenges. Despite huge demand, the African region is dependent on imported medicines and other health technologies. Although there is a high requirement for treatment, poor economic conditions lead to the slow growth of the healthcare industry within the African region. As per the statistics of the National Centre for Biotechnology Information (NCBI) in 2016, around 180 patients from West China Hospital who underwent excision of skin lesions, treated with cell therapy lived in low- and middle-income countries. This huge population affected with the chronic diseases in developing countries serves as a strong opportunity for key players operating in the tissue engineering market.
Although tissue engineering is an emerging field, there is low awareness about the technology among healthcare professionals in emerging economies. While there is a huge scope for tissue engineering in the healthcare industry, the practical implementation of its applications is yet to be derived. Additionally, in case of 3D bioprinting technology of tissue engineering, 3D printers on a commercial scale are still to be developed on a large scale due to expensive nature of bioprinter, lack of awareness, and scalability of machines. Therefore, the lack of awareness regarding tissue engineering and its applications inhibit market growth in emerging economies.
Tissue engineering is majorly trending in the fields of 3D bioprinting. 3D bioprinting plays a key role in the field of personalized medicine. Advancements in computer-aided design (CAD) and fabrication technologies have brought new trends in the 3D bioprinting field during the past few years. Biomimicry or biomimetics are also finding applications in the field of tissue engineering. Biomimicry is the imitation of models, systems, and elements of nature for solving complex human problems. These complex problems are solved in many ways when a biomimetic approach is utilized to bioprinting project design. Other trends include the use of tissue engineering in regenerative medicines and use of microfabricated tissue-engineered 3D models in research for cancer and other chronic diseases.
The price of tissue engineered products varies by a large margin in different regions of the world. The market for tissue engineered products is mainly concentrated in developed regions of the US and Europe. The price of tissue engineered products such as bone grafts, membranes, and cell lines, etc. is expected to be higher in the US as compared to Europe and significantly higher than the rest of the world. However, according to our research, the final cost of tissue engineered products is almost equal compared to the US and Europe due to the better reimbursement in the US. Good reimbursement scenario is essential to utilize the real market potential of tissue engineered products fully. For instance, many tissue engineering products have been viewed and listed as costly procedures in many regions. Thus, Germany is considered to have more restricted reimbursement policies than the US which increases the cost of the final tissue engineered product.
In addition to pricing by companies, there is a need of structural changes in the healthcare setup of a region such as specialized wound healing centers which are not present in developing regions of the world such as India and China. These specialized centers increase the volume of tissue engineered products which drives the final cost of these products due to economies of scale achieved. The market is smaller for tissue engineered products which do not heavily rely on the reimbursement policy of health insurances. Such products include tissue engineered products for aesthetic surgery and dental implants. These products have a low-cost difference in developed and developing regions.
The final price of the US is considered to be approx. 25% greater than in Europe. However, for low tech tissue engineered products developing regions may have a price advantage of almost 40% to 60 % of the price in the US.
In the past few years, the tissue engineering market has witnessed tremendous growth. The major propelling factors behind such rapid diversification are technological advancements and high demand for tissue engineering in various surgical procedures. In the past few years, the government has undertaken various initiatives to support technological developments in the field of tissue engineering. In the US, various federal agencies are providing strategic funding for R&D of tissue engineering. MATES (Multi-Agency Tissue Engineering Science), a consortium of federal agencies, monitors the joint sponsorship for scientific meetings and workshops, related to tissue engineering and sciences. The economic conditions of Japan towards tissue engineering are slowly becoming positive. The funding history in the US is more biased towards bioengineering aspects rather than biological aspects. The situation is not true in the case of Europe, as tissue engineering is still relatively new with emphasis on biological aspects. Globally, health systems are developing in response to multiple factors such as new medical technology, new health services, changes in health policies, new organizational structures, innovations in drug development, and great access to health services.
Market Size, Growth Rate, and Profitability
The global market for tissue engineering was valued at 20,375.05 million in 2018, and the market is estimated to reach 53,424.00 million by 2024, growing at a CAGR of 17.84% from 2019 to 2024. The tissue engineering market has an extremely high potential, and any novel product would have advantages in terms of profit margin, great value density, and cost-effectiveness of logistics due to high value and low volume of the treatment. The profitability and risks of different sectors of the global market for tissue engineering vary.
Investment Risks
Technological disruptions remain the most serious investment risks for the global tissue engineering market. The history of medicinal innovations for rare diseases is a witness to the power of disruptive research and innovation threatening existing market leaders. 3D printing is estimated to be the most disruptive innovation in this market. 3D printing has the potential to generate a functional bone graft within a few hours. Thus, choosing the right research approach is crucially more important than the research cost in the global tissue engineering market.
Financial risks include high risk of research uncertainty and political and humanitarian pressures to reduce the cost of any novel tissue engineering product which may be used in the treatment of important diseases. Other risks are currency volatility and the high fixed cost and operating costs imposing serious investment risks.
Market Outlook
The profitability of novel tissue engineering products will be high due to the low number of competitors in the market. The availability of advanced products in the market also confers significant market positioning and proposition in terms of the technologically-advanced image of the company. The global tissue engineering industry thrives on innovation and technologically-advanced products. This requires to position a company as the most advanced and innovative drug developer to tap the high cost and high growth of the novel drug segment. Thus, a first come, high take strategy will lead not only to fast market uptake and positioning but will also yield a high premium with minimum marketing cost. The industry also requires highly trained and comparatively expensive labors and skills.
Competitors
The competitor is a broad category which includes not only other companies but also other nations and even other technologies and substitutes. Thus, it would be myopic to see only other companies as competitors. Tissue engineering is a high technology industry with numerous applications. Therefore, all countries make every effort to develop their biotechnology and medical devices industries. In the last years, nations such as China and South Korea had been making every effort to develop their biotech sector. China has emerged as a manufacturing base for medical device companies due to its low cost and poor environment regulations and labor practices. China’s efforts to develop its biotech sector has shown good results in sectors such as vaccines and biological products. The same can be expected in the tissue engineering industry. The low-cost labor in developing regions coupled with the focus of these nations on the tissue engineering industry due to its positive effects on the entire biotech sector will drive the market for tissue engineering in these regions.
Projections
The global tissue engineering market is projected to rise by an impressive rate, driven by factors such as growing geriatric population, increasing incidence rate of chronic and infectious diseases, 3D bioprinting emerging as a novel tissue engineering strategy due to its cost efficiency, and increased focus of companies on tissue engineering-based therapies. It is expected that the global tissue engineering market will witness high growth during the forecast period.
Near-term growth will likely concentrate in modular bioreactor lines and closed-system media workflows that shorten validation cycles while preserving batch traceability.
Partnerships between CDMOs and instrumentation vendors should accelerate standard datasets for comparability across sites, improving forecasting models used in capacity planning.
Longer horizon, organoid and microphysiological adoption may reshape segment mix; teams that invest early in assay interoperability and cloud QC hooks are better positioned to capture upside without fragmenting their analytics stack.
Profiles of 107 companies operating in the Tissue Engineering Market market, including revenue, employee count, and market positioning where available.
Showing 107 of 107 companies
Organovo Holdings Inc.
Company Headquarters: San Diego, US Founded: 2007 Workforce: 115+ Company Working: Organovo Holdings Inc. is a leading biotechnology company which provides 3D bioprinting functional tissues. The company focuses on manufacturing three-dimensional tissues, and these tissues are used in various research and development activities as well as in implant therapies. Moreover, it depends on collaborations and strategic agreements with biopharmaceutical companies, research institutes, and healthcare providers to expand its business. Organovo Holdings Inc. provides products and services related to therapeutic tissues, high-quality human cells (samsara), and disease modeling platform that supports drug discovery and development.
Baxter International
Company Headquarters: Deerfield, Illinois, US Founded: 1931 Workforce: ~50,000 Company Working: Baxter International Inc. (Baxter) is a Fortune 500 American health care company with headquarters in Deerfield, Illinois, US. The company primarily focuses on products to treat hemophilia, kidney disease, immune disorders, and other chronic and acute medical conditions. Baxter is a leading producer of intravenous (IV) fluids and systems. It also manufactures infusion pumps, pre-filled syringes, biological sealants, and inhaled anesthetics, as well as dialyzers and other products for the treatment of end-stage renal disease. Its global footprint and critical nature of products and services play a key role in expanding access to healthcare in emerging and developed countries. These products are used by hospitals, kidney dialysis centers, nursing homes, rehabilitation centers, doctors’ offices, and patients at home under physician supervision. As of December 31, 2018, Baxter manufactured products in over 20 countries and sold them in over 100 countries.
Allergan
Company Headquarters: Dublin, Ireland Founded: 2013 Workforce: ~16,900 Company Working: Allergan is a leading global pharmaceutical company. The company is engaged in the manufacturing and commercialization of hyaluronic acid for medical products, devices, biologics, and surgical products for patients across the world. It operates through three business segments, namely US Specialized Therapeutics, US General Medicine, and International. The company sells its products primarily to the retailers and distributors including food store chains and national retail drug. The prime customers are hospitals, clinics, and government agencies as well as managed healthcare providers, such as health maintenance organizations and other institutions. The company has operations in 100 countries. The US and Canada account for around 10% of the company’s revenue. The three prominent customers of the company are McKesson Corporation, which accounted for around 25% of the sales revenue; Cardinal Health, Inc with 23%; and AmerisourceBergen Corporation with 22% in 2018. In addition, the company has development and manufacturing centers of raw materials, intermediate ingredients, and active pharmaceutical ingredients. Its manufacturing plants are located in Ireland, the US, Brazil, Belgium, France, and Costa Rica.
Zimmer Biomet
Company Headquarters: Warsaw, Indiana, (US) Founded: 1927 Workforce: 19,000+ Company Working: Zimmer develops, produces, and markets musculoskeletal healthcare products. It is a leading brand in providing customized joint and bone healthcare solutions. It offers products related to orthopedics, healthcare, medical instruments, medical technology, surgical instruments, medical supplies, medical devices, innovation, and signature solutions. The company is present in all major markets and holds significant market share in the global tissue engineering market.
DEPUY SYNTHES
Company Headquarters: Massachusetts, US Founded: 1895 Workforce: 18,000 + Company Working: DePuy Synthes is a subsidiary of Johnson & Johnson Services, Inc. The company is involved in manufacturing and marketing of orthopedic and neurological devices. It operates through business segments including joint reconstruction, trauma, spine, sports medicine, neuro, cranio-maxillofacial, power tools, and biomaterials. Additionally, it is engaged in manufacturing of reconstruction solutions for hip, knee, and shoulder replacement and trauma devices for internal and external fixation, implants, and instruments. It is directly present in more than 60 countries and operates in all major markets.
Acelity
Company Headquarters: San Antonio, Texas, US Founded: 1976 Workforce: 5,000+ Company Working: Acelity is a major market player in manufacturing and providing healthcare solutions related to the wound management. The company is into wound management, open abdomen management, incision management, epidermal harvesting, and animal health. Acelity is present in all major and emerging markets which include more than 90 countries. It concentrates on providing quality products and improving people’s health. The presence of Acelity in the global market is noticeable, and the company holds a significant market share.
8 interactive charts drawn from the Tissue Engineering Market dataset — market size, regional splits and each segment breakdown. Open one to read its full data table and download it.
Global Tissue Engineering Market Germany, Spain, France, United Kingdom, Italy and Eastern-Europe Of Europe By Country
Global Tissue Engineering Market Australia, China, India, Japan, South Korea and Rest Of Asia Pacific By Country
Global Tissue Engineering Market Middle-East and Africa Of Middle East And Africa
Global Tissue Engineering Market By Region
Tissue Engineering Market Europe By Country
Tissue Engineering Market Asia Pacific By Country
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