| Field | Detail | Source / note |
|---|---|---|
| Legal name | Evogene Ltd. | Form 20-F FY2025 cover |
| Former names | None at parent level identified. Subsidiary Casterra Ag Ltd. was historically linked to the company's castor activity previously associated with "Evofuel Ltd." (Evofuel remains listed as an entity chaired by the CEO) | MarketScreener insider profile; not confirmed as formal rename |
| Founded / incorporated | Incorporated 10 October 1999; founders Amir Barzilay and Hagai Karchi; operations commenced as a spin-off from Compugen Ltd. (CEO Ofer Haviv joined from Compugen as CFO in January 2002) | TradingView/CNN profile; 20-F FY2025 (Haviv biography) |
| Incorporation jurisdiction | Israel (Israeli Companies Law, 5759-1999) | 20-F FY2025 |
| Headquarters | 13 Gad Feinstein Street, Park Rehovot, Rehovot 7638517, Israel; Tel +972-8-931-1900 | 20-F FY2025 cover |
| Exchanges / tickers | Nasdaq Capital Market: EVGN; Tel Aviv Stock Exchange: EVGN | 20-F FY2025 |
| Security | Ordinary shares, par value NIS 0.2 (post 1-for-10 reverse split effected 24 July 2024) | 20-F FY2025 |
| ISIN | IL0011050551 | TradingView |
| CUSIP | n/d | — |
| SEC Commission File No. | 001-36187 (foreign private issuer; files 20-F / 6-K) | 6-K August 2026 |
| Filer status | Non-accelerated filer; not an emerging growth company | 20-F FY2025 |
| Fiscal year end | 31 December | 20-F |
| Shares outstanding | 8,718,193 (31 Dec 2025); approx. 12,103,764 (mid-2026, after February 2026 warrant inducement and ATM issuance) | 20-F FY2025; TipRanks (aggregator) |
| Employees | 117 (Dec 2024) → 38 (Aug 2026) | Q2 2026 release (via RTTNews) |
| Auditor | n/d in sources reviewed for this dossier (historically an Israeli Big-Four affiliate; verify against Item 16C of the FY2025 20-F) | — |
| Market capitalisation (current) | Approx. USD 6.6–10.0 million depending on date/price source; at ~USD 0.55 × ~12.1M shares ≈ USD 6.7M | Robinhood (21 Jul 2026: USD 6.59M); Motley Fool (USD 9.99M, undated); PitchBook (15 Jun 2026: USD 6.88M) |
| Listing status | Active, dual-listed; Nasdaq minimum-bid-price deficiency (compliance deadline extended to 29 March 2027) | 6-K / PR 30 Sep 2026 |
| Dividend | Never paid | Trendlyne / company |
The entity profiled is Evogene Ltd., the Israeli computational chemistry company headquartered in Rehovot, Israel, website www.evogene.com. This matches the name and type supplied: it is an active, publicly listed company (dual-listed on Nasdaq and the Tel Aviv Stock Exchange). No alternate entity needed to be substituted.
| Metric | FY2023 | FY2024 | FY2025 | Aug-2026 |
|---|---|---|---|---|
| Employees (headcount, period end) | — | 117 | — | 38 |
Aggregators show intermediate figures of 103 and 52, which are consistent with a progressive reduction during 2025–2026 but are not primary-source verified.
Evogene is a micro-capitalisation Israeli technology company that has spent 2025–2026 converting itself from a diversified "computational predictive biology" holding group — with subsidiaries spanning ag-biologicals, microbiome therapeutics, castor seeds, ag-chemicals and medical cannabis — into a narrowly focused generative-AI computational chemistry business. Its core asset is ChemPass AI™, a proprietary engine for designing and multi-parameter-optimising novel small molecules for pharmaceutical and crop-protection applications, built in part on a Google Cloud foundation model and now augmented with autonomous AI agents. Monetisation is collaboration-led (upfront, R&D, milestone and royalty economics, with Evogene retaining downstream rights) alongside an internal four-program drug pipeline and an ag-chemical pipeline run through subsidiary AgPlenus. The company has monetised non-core assets (Lavie Bio to ICL; BMC128 licensed to Lishan), cut cash burn by more than half, but remains revenue-light, going-concern-qualified, below Nasdaq's USD 1 bid-price threshold, and embroiled in an activist control contest.
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### Company's own description
In its current corporate boilerplate (press releases from late 2025 onward and the company website), Evogene describes itself as a pioneer in computational chemistry, specialising in the generative design of small molecules for the pharmaceutical and agricultural industries, with ChemPass AI™ — its proprietary generative AI engine — at the core of the offering, designed to produce novel, highly potent molecules optimised across multiple critical parameters, improving success rates while reducing development time and cost. The company labels its operating philosophy "Real-World Innovation", emphasising the integration of computation with industry partner needs (evogene.com/company).
The FY2025 20-F still describes the group structure as Evogene acting as a technology hub with divisions and subsidiaries beneath it that draw on the Computational Predictive Biology (CPB) platform and its engines (ChemPass AI and GeneRator AI), each subsidiary being responsible for its own pipeline, go-to-market and financing. However, the same filing makes clear that this hub-and-spoke model has been heavily pruned: Lavie Bio's activity was sold to ICL, Biomica was scaled down to complete one clinical trial, and Casterra and AgPlenus underwent dispositions and workforce reductions.
### Independent characterisation
Stripped of legacy framing, Evogene in October 2026 is best characterised as:
1. **An early-stage AI drug-discovery services-and-pipeline company** with six disclosed pharma discovery collaborations (biotechs and academic institutions), no clinical-stage proprietary small molecules, and internal programs at hit-to-lead / lead-optimisation stage. Preclinical work on internal candidates is guided to begin in 2H 2027 (Q2 2026 call).
2. **A small ag-chemical discovery business (AgPlenus)** with one surviving big-ag collaboration (Corteva, herbicides) after Bayer terminated its herbicide project in May 2026, and an internal wheat fungicide program (Zymoseptoria tritici / Septoria) in lead optimisation.
3. **A residual portfolio of monetised or wind-down subsidiaries** — Lavie Bio (asset-sold shell distributing cash), Biomica (licensed BMC128 to Shanghai Lishan; no ongoing operations; reported as discontinued from Q2 2026), and Casterra (castor seeds, realigned exclusively to Brazil).
Economically, the company is pre-commercial in its core business. Historical revenue has been dominated by non-core sources — Casterra seed sales and collaboration payments in Lavie Bio and AgPlenus — which are now shrinking or gone.
### Business and revenue model
| Revenue stream | Mechanics | Current significance |
|---|---|---|
| Discovery collaborations (pharma) | Partner brings biology/target; Evogene applies ChemPass AI to generate hits/leads; Evogene retains commercial rights/downstream economics to resulting discoveries | Strategic core; revenue contribution not separately disclosed and appears immaterial to date |
| Ag-chemical R&D collaborations (AgPlenus) | Upfront, R&D payments, development milestones, royalties (lower than pure licences) | Historically meaningful (Bayer one-time payment Q1 2024); Bayer project terminated May 2026; Corteva herbicide collaboration continues |
| Licensing of assets | Out-licensing of product candidates (e.g., BMC128 to Lishan) with potential future milestones/royalties to subsidiary | Economic value flows via subsidiary dividends (Biomica paid USD 2.7M dividend in Q2 2026; Evogene share ≈ USD 1.35M) |
| Product sales | Casterra castor seed sales to industrial (biofuel feedstock) buyers | Largest historical revenue driver in 2024–2025; declined sharply in 2026 |
| Asset monetisation | Sale of subsidiaries/tech engines (e.g., Lavie Bio + MicroBoost AI for Ag to ICL) | One-off; recognised in discontinued operations and dividends |
| Grants | Israeli Innovation Authority / EU grants netted against R&D | Offsets R&D (e.g., €1.2M EU grant to Ag-Seeds division announced 2024) |
Mix characterisation (FY2025, management commentary): the decline in revenue from ~USD 5.6M (restated FY2024) to ~USD 3.9M (FY2025) was attributed to lower AgPlenus milestone revenue, completion of the Corteva collaboration revenue stream recognised in 2024, and lower Casterra seed sales. Product sales (Casterra) therefore made up the majority of FY2025 revenue; licensing/collaboration constituted the balance. No subscription/SaaS revenue exists.
### Value-chain position, customers and end-markets
Evogene sits at the very front of the value chain — target-to-hit and hit-to-lead small-molecule discovery — upstream of preclinical development, clinical trials, regulatory approval and commercialisation, all of which it expects partners to carry. In agriculture it sits upstream of formulation, field development, registration (EPA etc.) and distribution, which are controlled by a consolidated oligopoly (Bayer, Corteva, Syngenta, BASF).
**Customer types:** biotech companies and academic drug-discovery centres (pharma); multinational crop-protection companies (ag); an industrial castor-seed purchaser (described in filings and calls as a major oil-and-gas company) and seed growers (Casterra).
**Customer concentration:** extreme. In H1 2025, one customer (Customer B, Casterra-related) accounted for 63% of revenue, another 14%, and a subsidiary shareholder 11% (6-K, H1 2025 interim statements). In 2021–2023 a single subsidiary shareholder accounted for 35%, 48% and 62% of revenue respectively (20-F FY2023).
**End-markets:** AI-enabled small-molecule drug discovery (immunology, neurology, oncology, metabolism per pipeline slide); crop-protection chemicals (herbicides, fungicides); industrial castor oil / biofuel feedstock (Brazil).